New computerized volume measurement method for optic nerve head (ONH) region comparison with measurements by Heidelberg SPECTRALIS optical coherence tomography
Year : 2020-06-01
Faculty : Allied Medical Sciences
Author : عبدالرزاق محمد سعيـد الحناوي /
Abstarct :
Purpose To introduce an innovative computerized methodology to calculate the volume of the optic nerve head (ONH) region from SPECTRALIS optical coherence tomography (OCT) images, a new parameter called as OCT ONH coronal volume is proposed. Method 47 OCT ONH examinations were obtained, 25 right eyes and 22 left eyes. For each OCT ONH examination, the automated diagnosis by OCT SPECTRALIS was also obtained. This included three parameters: retinal nerve fiber layer (RNFL) thickness, retina thickness, and ONH region's volume. The OCT ONH coronal volume - a new quantitative parameter - was reported for each OCT ONH test. It was generated from the 3D visualization of the OCT ONH surface morphology. Statistical observations between the new parameter and three other parameters were reported. Results The new parameter - ONH coronal volume – exhibited the capability to record the volume of the OCT ONH region. We proposed a new methodology to OCT machines, which required further assessment. The preliminary results showed that it is significantly different (p-value less than 0.001) from the ONH region's volume, which is calculated in OCT machines, so that it merits future prospective evaluation. Conclusions The calculation of the OCT ONH coronal volume is not only a new suggestive parameter to observe the OCT ONH region, but we also propose an innovative methodology for volumetric measurement of ONH region. Forthcoming research should validate the potential of the work.
Year : 2020-06-01
Faculty : Allied Medical Sciences
Author : عبدالرزاق محمد سعيـد الحناوي /
Abstarct :
Purpose To introduce an innovative computerized methodology to calculate the volume of the optic nerve head (ONH) region from SPECTRALIS optical coherence tomography (OCT) images, a new parameter called as OCT ONH coronal volume is proposed. Method 47 OCT ONH examinations were obtained, 25 right eyes and 22 left eyes. For each OCT ONH examination, the automated diagnosis by OCT SPECTRALIS was also obtained. This included three parameters: retinal nerve fiber layer (RNFL) thickness, retina thickness, and ONH region's volume. The OCT ONH coronal volume - a new quantitative parameter - was reported for each OCT ONH test. It was generated from the 3D visualization of the OCT ONH surface morphology. Statistical observations between the new parameter and three other parameters were reported. Results The new parameter - ONH coronal volume – exhibited the capability to record the volume of the OCT ONH region. We proposed a new methodology to OCT machines, which required further assessment. The preliminary results showed that it is significantly different (p-value less than 0.001) from the ONH region's volume, which is calculated in OCT machines, so that it merits future prospective evaluation. Conclusions The calculation of the OCT ONH coronal volume is not only a new suggestive parameter to observe the OCT ONH region, but we also propose an innovative methodology for volumetric measurement of ONH region. Forthcoming research should validate the potential of the work.